Improved sensitivity for two-photon frequency-domain lifetime measurement
نویسندگان
چکیده
منابع مشابه
Improved sensitivity for two-photon frequency-domain lifetime measurement.
We demonstrate a method to improve the measurement sensitivity of two-photon frequency-domain lifetime measurements in poor signal to background conditions. This technique uses sinusoidal modulation of the two-photon excitation source and detection of the second harmonic of the modulation frequency that appears in the emission. Additionally, we present the mathematical model which describes how...
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Jonathan D. Driscoll, Andy Y. Shih, Satish Iyengar, Jeffrey J. Field, G. Allen White, Jeffrey A. Squier, Gert Cauwenberghs, and David Kleinfeld Department of Physics, University of California at San Diego, La Jolla, California; Department of Statistics, University of Pittsburgh, Pittsburgh, Pennsylvania; Department of Physics, Colorado School of Mines, Golden, Colorado; and Department of Bioeng...
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متن کاملPhoton counting , censor corrections , and lifetime imaging for 1 improved detection in two - photon microscopy 2 3
3 Jonathan D. Driscoll, Andy Y. Shih, Satish Iyengar, Jeffrey J. Field, 4 G. Allen White, Jeffrey A. Squier, Gert Cauwenberghs and David Kleinfeld 5 6 Department of Physics, University of California at San Diego, La Jolla, CA 7 Department of Statistics, University of Pittsburgh, Pittsburgh, PA 8 Department of Physics, Colorado School of Mines, Golden, CO 9 Department of Bioengineering, Universi...
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ژورنال
عنوان ژورنال: Optics Express
سال: 2010
ISSN: 1094-4087
DOI: 10.1364/oe.18.013631